Madame Viper

Ophelia Sarkissian, also known as Madame Viper, Viper, or Madame Hydra, (voiced by Vanessa Marshall, Amanda Rea, and Mallory Jansen) is a villainess from the Marvel comics and one of the leaders of the terrorist organization, HYDRA. She is an enemy of Captain America, Spider-Woman, and the Avengers.